![]() These considerations provide the opportunity to develop a new and rigorous framework and classification of cardiomyopathies. 1 The past decade has witnessed a rapid evolution of molecular genetics in cardiology 9–14 and the emergence of ion channelopathies as diseases predisposing to potentially lethal ventricular tachyarrhythmias that are characterized by mutations in ion channel proteins leading to dysfunctional sodium, potassium, calcium, and other ion channels. 1 However, with the identification of several new disease entities over the past decade, dramatic advances in diagnosis, and precise knowledge of causation, some disease definitions have become outdated and render the WHO classification obsolete in many respects. The last formal effort at developing a consensus for a classification of cardiomyopathies was 11 years ago (1995) in the form of a very brief document under the auspices of the World Health Organization (WHO). However, many classifications offered in the literature and in textbooks are to some degree contradictory in presentation. Classification schemes, of which there have been many, 1–8 are potentially useful in drawing relationships and distinctions between complex disease states for the purpose of promoting greater understanding indeed, the precise language used to describe these diseases is profoundly important. The awareness of cardiomyopathies in both the public and medical communities historically has been impaired by persistent confusion surrounding definitions and nomenclature. Customer Service and Ordering InformationĬardiomyopathies are an important and heterogeneous group of diseases.Stroke: Vascular and Interventional Neurology.Journal of the American Heart Association (JAHA).Circ: Cardiovascular Quality & Outcomes.Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB). ![]()
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